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One notable feature of fungal enzymes is their low substrate selectivity, which, rather than being a drawback, proves advantageous ( Fungi display a remarkable range of enzymatic activities, segmented into intracellular and extracellular categories

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Research on HGF/c-Met signaling in other biological contexts demonstrates receptor internalization beginning around 4872 hours of sustained activation, with maximal downregulation occurring by day 57 of continuous agonist exposure