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doi: 10.1074/jbc.M901790200 261 TanimotoKMakinoYPereiraTPoellingerL
Gclc is required for T cell-independent and -dependent B cell immune responses Next, we aimed to understand how the metabolic perturbations caused by B cell-specific Gclc ablation impinge on immune responses and in particular how the impaired mitochondrial metabolism affects the antibody response
Interestingly, despite airway inflammation being a hallmark feature of asthma, it is not a requirement for asthma diagnosis, but instead helps to stratify disease severity
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