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The organization of cysteine residues confers distinct MT isoforms and their capacity to bind and sequester distinct HM ions for the purposes of detoxification and homeostasis (Ruttkay-Nedecky et al., 2013)

thus, appropriate tests need to be carried out to rule out this condition if suspected.[16] Therapeutic response to cyanocobalamin may decrease due to elderly age, infection, renal insufficiency, diabetes mellitus, marrow suppressants use (e.g