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Weight loss with CagriSema reached 15.6% versus 5.1% with semaglutide alone and 8.1% with cagrilintide alone, demonstrating clear superiority of the combination over either component

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SARS-CoV-2 mainly destroys pulmonary surfactant-secreting type II alveolar cells (Wang et al., 2021a), that normally decrease the air/tissue surface tension and block TLR4 in the lungs, promoting ARDS and inflammation