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GSTs catalyse the reaction of JS-K or PABA/NO with GSH to form a diazeniumdiolate anion that spontaneously decomposes, producing two equivalents of NO (Fig

Loren Pickart estimated that toxic effects would begin at approximately 22,500 mg, which represents a 300-fold margin above effective therapeutic doses

It affects various bodily functions, including: Sperm production Sex drive Muscle strength and size Deepening of the voice during puberty Bone growth and strength Growth of facial, body, and pubic hair during puberty Development of the penis and testes Testosterone may play a role in hair loss later in life

Users describe it as a "slow turn" rather than sudden improvement