A study published in the Journal of Dermatological Science found that overuse of these potent ingredients can disrupt the skin barrier, leading to increased susceptibility to environmental damage
DOI: 10.1002/ajh.10321 18
doi: 10.3389/fphar.2025.1719384 Received 06 October 2025 Revised 01 November 2025 Accepted 03 November 2025 Published 26 November 2025 Volume 16 - 2025 Edited by Gvozden Rosic, University of Kragujevac, Serbia Reviewed by Kandasamy Neelamegam, Tulane University, United States Ciniraj Raveendran, Government Medical College, India Updates Copyright 2025 Yan, Song, Zhang, Hu, Wang, Guo, Wang, Ma and Liu
Extended use may have adverse effects, despite the fact that they are non-invasive and helpful in the early stages of vitiligo