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It is suggested that high levels of DHEA have a beneficial effect on longevity and prevent several human pathologic conditions, including heart disease, diabetes, and chronic venous leg ulcers (Legrain and Girard, 2003

For T0901317 experiments, mice were injected intraperitoneally with either vehicle (10%DMSO in 90% corn oil) or T0901317 (MedChem Express, HY-10626) at a dose of either 16.9 mg/kg or 50 mg/kg dose for either 4 days (1720) days post AAV-TBG-Cre treatment) or 14 days (720) days post AAV-TBG-Cre treatment)

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A similar or greater dosage is used for research on nasal spray formulations