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In AD, decreased brain glucose uptake correlates with lower expression levels of the glucose transporters GLUT1 and neuronal GLUT3 [187,188,189], as well as with diminished activities of different metabolic enzymes such as glucose-6-phosphate isomerase, lactate dehydrogenase, phosphofruktinase, cytochrome oxidase, and -ketoglutarate compared to the controls [173,178,190,191]

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Localized injection-site discomfort in some research subjects Transient gastrointestinal or energy-related responses at higher exposure levels Rare metabolic odor changes reported in excess-exposure models Disclaimer: For research purposes only