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Silver nanoparticles combined with leaf extract have shown anticancer activity against HTC116 and SW480 cancer cells [206]

Regarding GSH, numerous research work verified the effectivity of this tripeptide as BBB targeting ligand of various vesicular [52,53,54] and poly(lactic- co -glycolic acid) (PLGA) nanoparticles [55, 56] in cell culture models, animals and in human studies as well

NO may also safeguard cells from oxidative processes by promoting the synthesis of GSH (Lu, 2013), in addition to its direct ROS scavenging activity and the modulation of lipid peroxidation through lipoxygenase (LOX) inhibition

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