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It may support fasting blood sugars and reduce insulin resistance

Patients with specific FTO or MC4R variants may respond better to combination therapy (such as dual semaglutide and tirzepatide) rather than semaglutide monotherapy

LPS, in particular, has been shown to increase the permeability of the BBB, allowing immune cells and inflammatory mediators to infiltrate the brain, exacerbating cognitive dysfunction (Takata et al., 2021)

Vitamin B12 deficiency has been associated with peripheral neuropathy and even cognitive deficits, especially in older adults and those with HIV/AIDS, where it supports nerve function and assists in the maintenance of myelin sheath integrity