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However, the functional role and the involved mechanism of SFN in psoriasis are not known and still need to be defined

At a normal therapeutic dose, acetaminophen is primarily metabolized by the liver to sulfate and glucuronide conjugates, while a SMALL amount is metabolized by CYP2E1 to a highly reactive intermediate, N-acetyl-p-benzoquinone imine (NAPQI)

doi: 10.1016/j.freeradbiomed.2011.01.026 49 WollerSAHookMA

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