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Healthcare professionals and patients should be aware that individual responses may differ significantly from trial averages, and that fatigue persisting beyond a few weeks or worsening at any stage warrants clinical review

(2014) Glutathione S-conjugates as prodrugs to target drug-resistant tumors, Front

Macrophage polarization modulates development of systemic lupus erythematosus

Relevant in vivo and in vitro experiments have confirmed that IGFBP-L1 methylation exerts a pro-oncogenic effect by promoting PI3K/AKT phosphorylation and IGFBP-L1 methylation has become a potential marker for the early detection of esophageal cancer, as well as a predictive marker for PI3K-targeted therapy in esophageal cancer (85)