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Insulin is a hormone that controls blood sugar levels, and in people with type 2 diabetes, the body becomes resistant to insulin, which makes it harder to control blood sugar

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Collectively, this dual metabolic identity, preserving physiological specialization in citrate production while hijacking polyamine and citrate pathways for oncogenic rewiring, not only distinguishes PCa from other malignancies but also unveils targetable vulnerabilities for diagnostic and therapeutic innovation

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