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Blind cage coding and automated video analysis (EthoVision, TopScan) are recommended Too low n : prior power analysis, n 8 minimum for rodent behavioural tests No positive control : without memantine, donepezil or scopolamine depending on the paradigm, impossible to judge if the model is functional No dose-response : a single tested dose is insufficient to conclude

During digestion, it needs to be released from this matrix to become available for absorption

Immediate medical attention is required if an allergic reaction happens

No baseline documentation: without pre-protocol photography, patients lose their reference point