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A 2022 study found that most people regained about of the weight they lost within a year after stopping the medication

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WD increased, whereas GE2 reduced, body weight in both sexes As expected, four weeks of WD consumption resulted in weight gain, compared to SD in both sexes (F( 1, 132 ) = 18.895, p 2 = 0.125, p = 0.000

Second, treatment discontinuations due to side effects were below 4% across the datasets, compared with 6.9% for the Wegovy Pill, while nausea and vomiting rates were broadly similar