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GLP-1 receptor agonists were originally developed to help patients with type 2 diabetes manage their blood sugar levels

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Taking the weight loss medication semaglutide did not increase the risk of depressive symptoms, suicidal thoughts, or suicidal behavior in persons without known major mental health disorders, according to a new study led by researchers from the Perelman School of Medicine at the University of Pennsylvania published this week in JAMA Internal Medicine

Note expressions are mainly in endoneurial macrophages and monocytes