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Contact your GP if tiredness persists beyond 46 weeks, significantly impairs daily activities, is accompanied by frequent hypoglycaemia, signs of dehydration, unexplained weight loss, mood changes, or symptoms suggesting sleep apnoea such as excessive daytime sleepiness

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Randomised, phase 1, dose-finding study of MEDI4166, a PCSK9 antibody and GLP-1 analogue fusion molecule, in overweight or obese patients with type 2 diabetes mellitus

Weight Loss Goals : The desired amount of weight loss can influence the choice of medication