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5 Here we summarized the complex mechanisms of GLP-1RAs and their latest advancements in treating various diseases, such as musculoskeletal inflammation, obesity, cardiovascular diseases, NAFLD, neurodegenerative diseases, and various cancers
It mimics a fragment of the native gastric protein, which may allow it to interact with receptors involved in tissue repair without provoking a strong immune response
These core mechanisms include the synthesis of short-chain fatty acids (SCFAs) and vitamins, the promotion of immune system maturation, and the competitive exclusion of pathogenic microorganisms [35, 36]