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"Continued Treatment With Tirzepatide for Maintenance of Weight Reduction in Adults With Obesity: The SURMOUNT-4 Randomized Clinical Trial." JAMA , vol
two published tirzepatide case series (Naranjo "probable"), FAERS reporting odds ratio 22.55 for allodynia across GLP-1 with tirzepatides neuro-AE proportion lower than semaglutides, class cohort signal (aHR 2.15) in related agents
Healthcare providers should establish clear communication channels for patients to report concerns and should conduct regular follow-up assessments, particularly during dose titration periods when adverse effects are most likely to emerge
If you experience recurrent vomiting during treatment, speak to our clinical team about whether additional contraceptive precautions are advisable during that period
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