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Very high baseline A1C and long-standing diabetes Pre-existing diabetic retinopathy or macular edema Concurrent insulin therapy Large and rapid A1C reductions over a short period Additional vascular risks such as high blood pressure, high cholesterol, kidney disease, or sleep apnea Improving glucose control remains important for long-term eye health

Side Effect Management GLP-1s may cause digestive side effects like nausea, vomiting, or constipation

From there, your provider may increase the dose in 2.5mg increments every four weeks based on response and tolerability

Having a physician assistant at the helm rather than a marketing executive or tech entrepreneur suggests a clinical orientation from the start