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One study published in the journal Neuroscience Letters demonstrated that a Dihexa supplementation treatment improved motor and cognitive function and protected against dopaminergic cell loss in a Parkinsons disease aged rat models
In order to further characterize this effect, -Glu-Glu was then tested on cells expressing either of GluN1 and GluN2A or GluN1 and GluN2B NMDAr subunits, bearing in mind that they are the most abundant NMDA receptors found in the hippocampus ( NMDA receptors were expressed first in astroglioma C6 cells
B 12 , 3187 (2022)
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