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Many patients in the trial were also receiving standard-of-care therapies for their underlying cardiovascular disease, with 90.1% of patients taking lipid-lowering medications, 86.2% antiplatelets, 70.2% beta-blockers, 45.0% ACE inhibitors and 29.5% ARBs

While B12 is generally safe, using it as a substitute for a prescribed GLP-1 medication means the patient is not receiving the actual treatment they need for weight management or blood sugar control

Patient reports and post-marketing surveillance data suggest that bloating is a relatively common experience, particularly during the initial weeks of treatment

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