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48 Langlois and colleagues 48 investigated the relationship between serum IGF-I and bone mineral density from the Framingham Heart Study, and reported that IGF-I levels were positively correlated with aBMD at all sites of the hip, radius, and lumbar spine in women, whereas IGF-I was not significantly associated with bone mineral density in men

The combination of quercetin and dasatinib may specifically induce apoptosis of senescent TECs, therefore restoring renal function and ameliorating fibrosis ( In vivo study has revealed that senolytic therapy of quercetin and dasatinib improved renal artery stenosis by reducing the p21 positive stenotic TECs and attenuating mesenchymal transition ( 4.5 Other renal disorders Dietary intake of the flavonoid quercetin has been proven effective in lowering blood pressure and restoring endothelial dysfunction in animal models of hypertension