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Researchers seeking the authorized drug for any clinical purpose should consult a licensed Canadian prescriber

The SURPASS-2 trial directly compared the two for type 2 diabetes and found tirzepatide superior at all dose levels

Several ophthalmologists and public health advocates are now urging the agency to require a black box warning on semaglutide drugs, including Ozempic, Wegovy, and Rybelsus, in light of mounting evidence linking them to nonarteritic anterior ischemic optic neuropathy (NAION)