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A., Wilkinson, J
As emphasized by Varma and colleagues, traditional single-layer kill-switch mechanisms often exhibit instability and may lose functionality within days, whereas multilayered systemsparticularly those combining CRISPR-inducible modules, toxinantitoxin systems, and synthetic auxotrophiesdemonstrate markedly greater robustness, maintaining containment across hundreds of generations (Varma et al., 2025)
Rice ascorbate peroxidase gene family encodes functionally diverse isoforms localized in different subcellular compartments
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