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The United Kingdom has seen soaring demand for GLP-1 drugs, with NHS shortages making the need for next-generation treatments even more urgent

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A 2-compartment model was selected as the base PK model based on AIC values and diagnostic plots (Figure 1)

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(A): the total time spent in social interaction, (B): the number of these interactions

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Indeed a review article concluded that in prospective trials, therapeutic doses of paracetamol do not cause toxicity, and notes that only in retrospective studies does therapeutic toxicity occur and this is likely due to the biases inherent in retrospective analysis [2, 6, 7]

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