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Experimental data on animal models have suggested that GIP suppresses peripheral arterial remodeling, thus showing an anti-atherosclerotic activity, by acting on receptors in the heart and vessels." Outcomes of clinical trials The first clinical trial to test the clinical efficacy of TZP was the SURPASS program, a six-stage trial conducted on three separate cohorts Japanese (SURPASS-J), Asian-Pacific (SURPASS-AP), and the cardiovascular outcome trial (SURPASS-CVOT)

[DOI] [PubMed] [Google Scholar] 20.Jehle P.M., Schulten K., Schulz W., Jehle D.R., Stracke S., Manfras B., Boehm B.O., Baylink D.J., Mohan S

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