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Participants Postmenopausal women, with no cardiovascular disease, liver or kidney disease, gastrointestinal disorder, including stomach ulcer or erosions, cancer, diabetes, musculoskeletal disease, and other severe chronic diseases were recruited through local advertisements
IGF-1 signalling studied for downstream growth-factor effects
Recommended protective habits include: broad-spectrum sunscreen protective clothing avoiding peak sun hours Without sun protection, melasma treatments may be less effective
Once reconstituted, maintain at 28C and protect from excessive heat, moisture, and direct light
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