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Pharmacokinetic studies reveal that merely 0.1% of the ingested EGCG dose reaches detectable levels in the bloodstream at its peak concentration time (Tmax) in healthy individuals (39, 199)

Because DSIP has not been thoroughly studied in humans, people who are pregnant or breastfeeding, have significant medical conditions, or take multiple medications should avoid using it unless advised by a qualified healthcare professional

Notably, some proteins associated with a stress response (NRF2 targets) remained upregulated in roseoflavin-treated cells (Extended Data Fig

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