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positively associated with intestinal motility in patients with chronic constipation,71 while a 2021 study determined that 1 billion CFU/day of DE111 significantly improved gastrointestinal [GI] discomfort, including constipation and diarrhea, in people with occasional GI irregularities.72 The postbiotic Lactobacillus casei 327 (25mg) plays an important supporting role

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instead, its proposed mechanism involves multiple downstream effects mediated by copper coordination chemistry and tripeptide-specific interactions with various proteins

Akhtar A, Shakir M, Ansari MS, Divya, Faizan MI, Chauhan V, et al