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DMPs associated with MAPK and mTOR signaling pathways were extracted for Gene set enrichment analysis (GSEA) using the clusterProfiler package, based on log-fold changes aggregated at the gene level from DMP results

Study 1 ( N = 607) aimed to understand stigma directed at individuals who lose weight using GLP-1s, so the target was described as either: having lost weight by using a GLP-1, having lost weight via diet and exercise, or not having lost weight

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If approved for both obesity and diabetes indications, Medicare patients with diabetes may get coverage while those with obesity alone are excluded