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The use of buthionine sulfoximine, which inhibits gamma-glutamylcysteine synthetase, has been investigated in animals as a method to decrease GSH

Reconstitution Steps Draw 3.0 mL bacteriostatic water with a sterile syringe Inject slowly down the vial wall to prevent foaming Gently swirl until fully dissolved (do not shake) Label vial and refrigerate at 28C Protect from light Important: This guide is for educational purposes only and is not medical advice

Clin Transl

The reduction reaction is catalysed by redoxin enzymes, such as TRXs and GRXs that transfer reducing equivalents from the PET chain as well as from NAPDH, GSH, and ascorbate