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The analysis, conducted by researchers from the University of Oxford and supported by the National Institute for Health Research (NIHR) Oxford Health Biomedical Research Centre and the Medical Research Council, revealed that taking the drug, a popular medication for type II diabetes, had no increased risk of adverse neurological or psychiatric outcomes compared to other antidiabetic medications, challenging recent concerns about the drugs safety

Metformin may modestly help preserve lean mass through its effects on AMPK activation in muscle tissue, though the evidence for this is preliminary

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These ROS influence cell function through DNA and protein fragmentation