While EC 1669 itself is cleared rapidly from the blood with an elimination half-life of -37 min, the elimination half-lives of the two metabolites are approximately 2-3 times longer at 66 min (AMT) and 112 min (EC0470), respectively
Side effects such as nausea, vomiting, and diarrhea are dose-dependent and similar across formulations
Disclosures Alan Kaplan has conflicts in being either a member of an advisory board or speakers bureau of the following companies: Astra Zeneca, Behring, Boerhinger Ingelheim, Cipla, Covis, Eiasi, GSK, Merck Frosst, Novartis, Novo Nordisk, Pfizer, Sanofi Genzyme, Teva, Trudel, Valeo
Patients were evaluated before (T0) and after six months (T6) from GLP1-RA initiation