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In one trial, 16 people placed on experimental bed rest for 3 weeks (in order to increase urinary calcium excretion by causing bone breakdown) and treated with 20 mg per day of the bisphosphonate alendronate had lower urine calcium concentrations, and lower calcium oxalate and calcium phosphate saturations, compared with placebo (Ruml 1995)

A study in rats found that BPC 157 counteracted the effects of an induced myocardial injury and significantly decreased oxidative stress

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Conversely, within the group of 28 patients new to treatment, the general response rate was 68%, with a median response time of 12.6 months [27,28,29]