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CA1 hippocampe neurons, which could be morphologically identified, were selected for evaluation because of their known plastic response during learning

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body weight: 22-24 g) are allowed ad libitum access to normal diet and water for 2 weeks before dividing into four groups (n=8): normal diet (ND) (10% energy from fat), high-fat diet (HFD) (60% energy from fat) and HFD plus -Lipoic Acid (100 mg/kg or 200 mg/kg)

Significant weight loss achieved with these agents may indirectly affect menstrual regularity, but the medicines themselves do not have an established direct effect on the menstrual cycle per their UK SmPCs