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Sex-differential dna methylation and associated regulation networks in human brain implicated in the sex-biased risks of psychiatric disorders

Factors such as chronic stress, poor diet, environmental toxins, excessive alcohol consumption, and certain medications can accelerate this decline

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As increased mitochondrial levels of glutathione (GSH) might contribute to a change in seizure susceptibility, we quantified changes of absolute GSH levels in the brain by in vivo 1H magnetic resonance spectroscopy (1H MRS) and correlate that with degree of seizure control in patients on KD