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Published pre-clinical studies have used FOXO4-DRI to demonstrate that selective elimination of senescent cells in aged mouse models can improve a range of tissue function parameters including fitness, fur density, renal function, and liver function establishing the broader research principle that senescent cell burden contributes meaningfully to ageing tissue dysfunction and that its targeted reduction produces measurable functional benefits in experimental models

*Correspondence: Dirin Ukwade [email protected] These authors share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Peptides used at Thrive are compounded in licensed pharmacies and are selected based on safety profiles and clinical use

Injecting it bypasses the pituitary entirely the body receives exogenous GH regardless of its own signaling state