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Therefore, one of the primary focuses of regenerative medicine research is identifying and understanding mechanisms that distinguish healthy regeneration processes, which lead to restoration of normal tissue architecture, and pathological processes, which may result in chronic inflammation, scarring, fibrosis or cancer

This combined activity has made it a valuable subject in preclinical research focused on receptor signalling, glucose-related pathways, lipid metabolism, energy expenditure, and broader metabolic regulation

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Global access further complicates implementation, as advanced biologic therapies such as stem cell patches demand specialized facilities and cold-chain logistics, limiting adoption in resource-limited settings