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Through a thorough analysis of scholarly literature, we discuss traditional prediction methods anchored in physiological parameters (e.g., heart rate, respiratory frequency, blood pressure) and biochemical markers, as well as the integration and utility of novel technologies such as biosensors, genetic testing, and artificial intelligence within high-altitude prediction research

Proc Natl Acad Sci USA 98:19641969

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Furthermore, while most findings indicate lower melatonin levels during NS compared to DS, some variability arises due to factors such as seasonality and specific shift schedules 173,193