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Gao M, Deng J, Liu F, et al

Pharmacodynamic study in DIO mice Female DIO mice with a body weight approximately 22 g received tail vein injections of either saline (Saline), scExe4 donor plasmid loaded LNP only (Donor), or scExe4 donor plasmid loaded LNP plus Cas9 plasmid loaded LNP (Donor+Cas9)

Korean J Physiol Pharm

The challenge, as we will see in the clinical evidence section, is translating that theoretical appeal into measurable real-world results at a magnitude that matters