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With research deepening, researchers focused on EMs and found that in the VK2/E6E7 and End1/E6E7 cell lines, naringenin targeted the MAPK and PI3K pathways in a dose-dependent manner

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Specifically, the use of chemotherapy drugs resulted in elevated levels of ALT and AST, and an increase in the severity of side effects such as nausea and vomiting, contributing to high GSH intake