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In a primary culture of orbital fibroblasts from GO patients and control subjects treated with H 2 O 2 to induce OS, the antioxidants vitamin C, N-acetyl-L-cysteine, melatonin, retinol, -carotene and vitamin E were found to reduce the manifestations OS (proliferation of fibroblasts, the level of hyaluronic acid, the level of tumor necrosis factor- (TNF-), IFN- and IL1-, which provided the basis for the possible clinical use of these substances in patients with GO (87)

A acetil-L-carnitina aumenta os nveis de energia e melhora as capacidades cognitivas

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Histopatologa Las mculas melanticas labiales, se caracterizan por una hiperpigmentacin focal de la hilera basal del epitelio de la mucosa que se acompaa de un nmero normal de melanocitos o slo un discreto aumento de estas clulas a lo largo de la interfase entre epitelio y el corion de la zona de la mucosa afectada