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Corneal confocal microscopy is a promising new noninvasive diagnostic tool that provides objective quantification of small nerve fibers in the subbasal layer of the cornea, which holds the densest concentration of these fibers (Figure 2)

In addition, melatonin stimulates neurogenesis and cell multiplication via a mechanism that relies on the MT2 receptor (Chern et al

From a drug development perspective, the key research question is how the screened drug candidates bind to their target proteins to produce their pharmaceutical effects

Table 2 illustrates various sources and types of polyphenols, along with their anti-inflammatory properties and modes of action