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Moreover, the significant implications of NRF2 hyperactivation, KEAP1 mutations, and BACH1 stabilization in cancer initiation, progression, and therapy resistance highlight the promising prospects of targeting the NRF2BACH1 signaling axis for therapeutic interventions in cancer management

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283 EGFR signal transduction requires a special endoplasmic reticulum Trx to control receptor expression on the cell surface

Given that inositol administration is safe and effective in ameliorating the reproduction and metabolism of patients with PCOS, it may be used not only as a treatment for infertile women but also as a preventive treatment during pregnancy [180,181,182,183]