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The clinical significance was highlighted by Lilly's leadership: "Obesity is a chronic, progressive disease, and sustaining weight loss remains a significant challenge for many," said Kenneth Custer , Ph.D., executive vice president and president, Lilly Cardiometabolic Health

Thus, following the example of cancer, drug therapy could precede bariatric surgery in order to render it safer and more feasible, but could also follow if the results are not satisfactory

Occasionally it can cause abdominal pain and gastrointestinal disorders

If that is still too expensive, metformin at $4-10 per month provides modest but real benefits, and phentermine at $15-30 per month offers the cheapest significant appetite suppression available