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Consistently, the STEP (Semaglutide Treatment Effect in People with Obesity) trial [22] demonstrated that after 68 weeks of semaglutide therapy in individuals who are overweight or obese, the average weight loss achieved was 14.9%, with 86.4% of participants achieving a reduction of at least 5% from baseline, and 69.1% and 50.5% achieving reductions exceeding 10% and 15%, respectively

Based on cystoscopic findings, interstitial cystitis can be classified based on severity from mild to severe.3 The discomfort that builds up due to bladder irritation can cause stress, fixation on the condition, and worry about recurrence, leading to anxiety and impairing the quality of life for people living with moderate to severe interstitial cystitis

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Endocrinology 162:bqab091 Gorini F, Vassalle C (2022) Selenium and selenoproteins at the intersection of type 2 diabetes and thyroid pathophysiology