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The milk thistle/Silymarin reduces oxidative stress caused by hydrogen peroxide as well as increases the antioxidant activity of various antioxidant enzymes including GPX1

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Although the CR group exhibited significantly lower lumbar spine and hip BMD compared to controls, there were no significant differences in serum CTX, bone-specific alkaline phosphatase (BSAP) levels, or trabecular microarchitecture parameters (e.g., erosion index, surface-to-volume ratio) between the groups