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The cause of vitamin B12 insufficiency is complex and poorly understood, involving the altered vitamin B12s enterohepatic circulation, decreased IF (Intrinsic Factor) secretion, bacterial overgrowth, and interference with the calcium-dependent coupling of IF-vitamin B12 complex to the cubilin receptor

For years, these therapies were available only as injectable formulations, requiring weekly or daily subcutaneous injections

The availability of both short and long-acting formulations allows for flexible dosing regimens depending on patient needs

2025, www.novonordisk.com/content/nncorp/global/en/news-and-media/news-and-ir-materials/news-details.html?id=916472