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Bichler and coworkers showed that the consumption of 600 mL coffee (400 mL paper filtered and 200 mL metal filtered/day) for 5 days reduced both endogenous (FPG and Endo III-sensitive sites by 64% and 48%, respectively) and oxidatively induced DNA damage (measured as DNA resistance to H 2 O 2 and Trp-P-2 by 17% and 35%, respectively) in a group of healthy volunteers [47]

10.3389/fphar.2019.00252 222 RegelmannW

So, if it cannot be fermented, it causes inflammation